Watch for indications of urinary retention or lessened gastric motility if oliceridine is coadministered with anticholinergics.Outcome of coadministration of a twin CYP3A4 and CYP2C19 inhibitor with fedratinib hasn't been analyzed.topiramate will reduce the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. U